The Arizona Cardinals (1-2) and the San Francisco 49ers (3-0) will battle on Sunday afternoon. Arizona earned their first win of the season in last week’s 28-16 win over the Dallas Cowboys. The Cardinals ran for 222 yards in the victory. Meanwhile, San Francisco won again in Week 3, taking down the New York Giants 30-12. The 49ers held the Giants to just 150 yards of offense in the blowout.
Cardinals vs. 49ers Betting Odds
Team | Money Line | Spread | Over/Under |
Arizona Cardinals | +600 | +14 (-110) | Over 43.5 (-110) |
San Francisco 49ers | -900 | -14 (-110) | Under 43.5 (-110) |
Odds courtesy of BetRivers Sportsbook
Match Details
Fixture: Arizona Cardinals @ San Francisco 49ers
Date & Time: Sunday, October 1, 4:25 p.m. EDT
Venue: Levi’s Stadium in Santa Clara, CA
Key Stats
The Arizona Cardinals have struggled to push the ball downfield in 2023. Despite being in the bottom ten in passing yards and passing touchdowns, more importantly, they have yet to throw an interception this season. Behind running back James Conner, the Cardinals rushing attack has been excellent. Conner averages nearly 90 rushing yards per game on 5.2 yards per carry. Meanwhile, quarterback Joshua Dobbs has 93 rushing yards and a score this season.
The Cardinals’ defense is 26th in yards allowed but 15th in points allowed (22.3). They have allowed just four passing touchdowns while forcing three interceptions. However, opposing backs are averaging 4.6 yards per attempt.
San Francisco has a respectable passing offense. Quarterback Brock Purdy has thrown for 736 yards and four scores with no interceptions. He has completed 67% of his passes. The rushing offense is elite, averaging 4.8 yards per attempt on 101 attempts. Running back Christian McCaffrey continues to shine in Kyle Shanahan’s offense, rushing for 353 yards and three scores across his team’s first three games.
Defensively, the 49ers have one of the best secondaries in the NFL. San Francisco has forced five interceptions while allowing just two passing touchdowns this season. The rush defense is equally impressive, holding opposing backfields to just 3.7 yards per attempt.
Cardinals vs. 49ers Betting Prediction
I like the Cardinals to cover in this Week 4 contest. Arizona has played tough to start the Jonathan Gannon era, especially on defense. Meanwhile, although the San Francisco 49ers have been excellent on both sides of the ball, winning big in divisional games is always challenging. So, let’s roll with the Cards to cover in this Sunday tilt.
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