The San Francisco Giants (74-70) host the Cleveland Guardians (68-77) on Tuesday night for the second game of this three-game set. The Giants won the opener on Monday, 5-4, their fourth victory in a row. The Guardians have now lost three straight, and seven of their last nine, putting them 7.5 games behind the AL Central-leading Minnesota Twins. The Giants are just 1.5 games back of the final NL Wild Card spot, and they’ll look to stay hot tonight.
Guardians vs. Giants Betting Odds
| Team | Run Line | Over/Under | Money Line |
| Cleveland Guardians | +1.5 (-142) | Over 8.5 (-108) | +150 |
| San Francisco Giants | -1.5 (+120) | Under 8.5 (-112) | -180 |
Odds via DraftKings Sportsbook
Guardians vs Giants Match Details
Fixture: Cleveland Guardians @ San Francisco Giants
Date and Time: Tuesday, September 12, 9:45 p.m. EST
Venue: Oracle Park, San Francisco, CA
Key Stats
San Francisco’s Sean Manaea gets the call tonight. The lefty is 5-5, with a 5.00 ERA through six starts and 27 relief appearances. Manaea has been a starter for the majority of his career, but this will be his first start since May. We’re not sure how long he’ll go, but the Giants bullpen isn’t bad, which can back him up. The Guardians don’t have the strongest lineup around, and they’re really slumping now, averaging under three runs per game over the past week. Manaea has been shaky, but Cleveland is ice cold at the plate right now, which could help the veteran left-hander.
Cleveland is going with Cal Quantrill, who is 2-6, with a 5.70 ERA. The righty has really struggled this year after an excellent three-year stretch, which is disappointing. San Francisco’s offense has been hot on this winning streak, and with Quantrill’s poor stats, they should be able to hit him pretty hard.
Guardians vs Giants Betting Prediction
San Francisco is a very streaky ballclub, and at the moment, they’re hot. Prior to this four-game winning streak, they lost six in a row, so they definitely rely on momentum. Cleveland has lost six of Quantrill’s last seven outings, and they’re a rough 32-41 on the road. Back the Giants here to win by at least two runs to clinch the series victory.
